Classified by the Carnegie Foundation as a Category 1 research university and is one of only a dozen universities in the US designated as a Land, Sea and Space grant college. It is the principal U.S. institution of higher education and the only Research Centers in Minority Institutions (RCMI) grantee institution within the Pacific basin. Biomedical research at UHM has been strengthened with the movement towards creating a research-intensive medical school, the John A. Burns School of Medicine (JABSOM) with many biomedical research initiatives centered in JABSOM, which serves as the administrative home for RCMI, RCRII, CCRE, COBRE, CRECD, SNRP, AIDS SNRP, ACTU, and EXPORT. This concentration of biomedical research activity has spawned interdisciplinary collaborations between JABSOM faculty and faculties from various units within the Manoa campus, especially with the College of Natural Sciences (CNS), the School of Ocean and Earth Science and Technology (SOEST), the College of Tropical Agriculture and Human Resources (CTAHR), the Water Resource Research Center (WRRC), and the College of Engineering (COE). The Hawaii INBRE II is a program specifically intended to enhance the caliber of scientific faculty at research institutions and undergraduate schools and to increase the competitiveness of researchers from Hawaii. The current program was designed to build on the successes of the first INBRE. To achieve our goals, the resources provide a pipeline of qualified students interested in careers in the Biomedical Sciences. This network includes researchers from UH Manoa, the UH Hilo College of Pharmacy, Chaminade University and Hawaii Pacific University.