Multi-Site Pilot Project

Clinical and Translational Research Infrastructure Network (CTR-IN) Funding Opportunity Announcement (FOA): Multi-Site Research Project Program

Overview: The Clinical Translational Research Infrastructure Network (CTR-IN) is supported by the National Institute of General Medical Sciences (NIGMS) under the Institutional Development Award (IDeA) program for development of clinical and translational research (CTR) capacity among our partner Mountain West IDeA states. One of the long-term CTR-IN goals is to build collaborative CTR projects engaging multiple researchers and institutions across the Mountain West Region to address critical regional health disparities issues. Multi-Site Research Projects (MSRP) can be transformative in the Mountain West by overcoming obstacles related to our small and rural populations as well as issues related to institutional infrastructure support for clinical research. The long-term goal is to build extramurally-funded collaborative CTR projects engaging researchers and institutions across the Mountain West Region to address a critical regional health disparities issues. The purpose of this FOA is to provide pilot project support for a multi-site CTR health disparities project with the expectation that this project will yield the key preliminary data to facilitate a large-scale multi-site extramural grant application.

Eligibility to lead Multi-Site Research Project:

  • A successful proposal will describe a CTR project directed by a Lead Investigator with a faculty appointment at a Mountain West CTR-IN institution.
  • The Lead Investigator must have a track record of extramural funding for clinical research in the area of the proposed research project.
  • The Lead Investigator may not concurrently serve as a Principal Investigator (PI) on another IDe Aaward (i.e., CTR, COBRE or INBRE).
  • The project must include at least two CTR-IN institutions,including the Lead Institution. For example, the project will include the Lead Institution/Lead Investigator and one or more collaborating Site Institution(s)/Site Investigator(s).
  • The collaborating Site Investigator(s) must have faculty appointment(s) at the partnering CTR-IN institution(s).
  • A CTR-IN Institution can serve as the Lead Institution for only one Multi-Site Research Project proposal but can be a Site Institution on multiple proposals.
  • Special Note: Given the short timing of this project, it is likely that the most successful and meritorious applications will be those that already have established cross-institutional partnerships and limited barriers to initiating the collection of clinical data. For example, applicants will be required to have IRB approval(s) in place before final award decisions are made.

 Funding Source: National Institute of General Medical Sciences (NIGMS, U54GM104944).

Key Dates:

Letter of Intent (required) Due Date 22 February 2017
Invitations to investigators to submit full applications will be issued by 01 March 2017
Application Due Date 17 April 2017
Award(s) Announcement 31 May 2017
Earliest Start Date 15 July 2017

Project Duration: One year (July 2017 through June 2018). No carryover beyond project period.

Process:
Letter of Intent.
Potential applicants (i.e., Lead Investigator) must submit a letter of intent by the date indicated above. The letter of intent should include the following –title of project; one-page summary of the proposed project that includes description of how the project addresses a health disparity; confirmation that the Lead Investigator is not currently serving as a PI on an IDe Aaward (i.e., CTR; COBRE; INBRE); list of investigators and CTR-IN institutions involved; and attached letter of support from the submitting institution’s Vice President for Research, or equivalent, indicating that this project has been selected as the single Lead Institution submission for this limited competition opportunity. [Note: As described above, a given CTR-IN institution can participate in multiple applications as a partner site under this announcement, but may submit only one application as the Lead Institution.]Letter of Intent should be emailed to Kathrene Conway (kathrene.conway@umontana.edu) by the date indicated above.

Invitation to submit full applications.
Applicants will be notified on or before the date indicated above if they are invited to submit a full application. At that time, CTR-IN will provide Lead Investigators with further details of the necessary forms and procedures for application.

Funding Level and Allowable Expenses:
Additional guidance on formatting budgets will be made available to applicants that are invited to submit a full application. For planning purposes, some preliminary budget guidance is provided below.

Overall budget:
We anticipate funding one to three projects under this announcement (pending NIGMS approval). Total costs of up to $150,000 may be requested. 10% F&A are allowable within the total cost cap. Budgets should be reflective of the scope of work and the number of institutions participating in the project. For a given award, separate subawards to each participating CTR institution will originate from the CTR-IN administrative office at UNLV.

Personnel effort:
There is no minimum level of effort required for Lead Investigator and Site Investigators. However, it should be clear that adequate effort by Lead and Site Investigators is devoted to the project in order to accomplish the goals. In other CTR-IN pilot funding mechanisms, institutions are required to support half of the investigator’s effort. This is not a requirement under the FOA.

All other expenses must be allowable under NIH guidelines. The following are not allowable for CTR-IN awards: Equipment costs over $5,000, significant foreign participation, and subcontracts to institutions outside the CTR-IN network.

Travel expenses are allowed for field work or to support investigator team meetings.

Budgets must include costs for the Lead and Site Investigators to attend the CTR-IN Annual Meeting in Las Vegas (May 2017).

CTR-IN Institutions:

  • Boise State University
  • Idaho State University
  • Montana State University
  • New Mexico State University
  • University of Alaska, Anchorage
  • University of Alaska, Fairbanks
  • University of Hawaii
  • University of Idaho
  • University of Montana
  • University of New Mexico
  • University of Nevada Las Vegas
  • University of Nevada Reno
  • University of Wyoming