Date: December 17, 2014
Time: 1:00PM PST; 2:00PM MST; 3:00PM CST; 4:00PM EST; 12:00PM AKST; 11:00AM HST
- Obesity is a worldwide epidemic
- Prevalence of sarcopenia occurs in 25-50% in individuals 60-80 years of age
- Inactivity exacerbates the problem
- Caloric restriction leads to muscle loss
- Unique clinical conundrum for older, overweight individuals
The older, obese individual represents a growing segment of the population that is faced with multiple health concerns. While obesity in itself is associated with an increased risk of diabetes and cardiovascular disease, dietary induced weight loss may exacerbate the potential for muscle wasting and physical disability.
As we age, these issues become increasingly challenging as adipose tissue accumulates and skeletal muscle begins to atrophy in what is commonly referred to as sarcopenic obesity.
Many clinical weight loss programs, even if available, are often not recommended due to the loss of skeletal muscle and the increased risk of mortality. We have recently determined that a meal replacement rich in amino acids (AAMR)promoted positive changes in muscle protein synthesis and functional status, even during conditions of short-term weight loss, advanced cancer and strict bed rest.
Utilizing a combined approach that includes dual energy x-ray absorptiometry and d3-creatine dilution, we hypothesize that the greater degree of anabolic efficiency exhibited by the AAMR will preserve lean tissue and skeletal muscle compared to the commercial meal replacement (CMR) in older, obese individuals.
Since the concomitant preservation of skeletal muscle and reduction of adipose tissue should improve glucose metabolism, we hypothesize that AAMR will promote improvements in insulin sensitivity as measured by a dual tracer + oral glucose tolerance test method.We also hypothesize that AAMR will promote greater improvements in strength and functional status compared to CMR. Therefore, the targeted changes in the body mass will help reduce physical disability and the risk of metabolic disease in the older, obese population.
Meet the presenter:
Robert H. Coker, Ph.D. FACSM
Associate Professor of Biology and Exercise Physiology
Principal Investigator, Center for Alaska Native Research,
Institute of Arctic Biology, University of Alaska-Fairbanks,
Co-Owner, Essential Blends, LLC
To participate in the webinar, you will be provided with a link to adobe connect (virtual classroom) after completing registration.
Click here to register for the WEBINAR: Muscle Preservation During Weight Loss in Older, Overweight Individuals.